The 11th Trial of a Cardiovascular Clinical Trialist
نویسندگان
چکیده
منابع مشابه
Implications of Contemporary Clinical Trials The Placement of Aortic Transcatheter Valve (PARTNER) Trial Clinical Trialist Perspective
For several decades, surgical aortic valve replacement (sAVR) has been considered the therapeutic gold standard for the treatment of severe aortic stenosis (AS). Severe AS is a progressive disease with a long latency period, and despite significant strides in medical therapy for numerous other forms of cardiovascular disease, little progress has been made in medical therapy for AS. The mechanic...
متن کاملThe Placement of Aortic Transcatheter Valve (PARTNER) trial: clinical trialist perspective.
For several decades, surgical aortic valve replacement (sAVR) has been considered the therapeutic gold standard for the treatment of severe aortic stenosis (AS). Severe AS is a progressive disease with a long latency period, and despite significant strides in medical therapy for numerous other forms of cardiovascular disease, little progress has been made in medical therapy for AS. The mechanic...
متن کاملConfessions of a chagrined trialist
As a clinical trialist, I had thought that the methods I employed were far more challenging than those I had thought were needed for quality improvement. However, some personal experiences and participation in the Cliveden conference led me to a new appreciation of the methodological and conceptual challenges faced by those trying to improve medical systems.
متن کاملClinical trialist perspectives on the ethics of adaptive clinical trials: a mixed-methods analysis
BACKGROUND In an adaptive clinical trial (ACT), key trial characteristics may be altered during the course of the trial according to predefined rules in response to information that accumulates within the trial itself. In addition to having distinguishing scientific features, adaptive trials also may involve ethical considerations that differ from more traditional randomized trials. Better unde...
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ژورنال
عنوان ژورنال: Cardiology in Review
سال: 2021
ISSN: 1061-5377
DOI: 10.1097/crd.0000000000000386